The Elcock Group

Molecular Simulations in Biology

Welcome

The Elcock group is a combined computational-and-experimental group that focuses on applying molecular simulation methods to understand biochemical and biological phenomena.

We wish that this website would work properly. But right now it’s something of a joke - especially if you’re using a non-Micro$oft browser. We’re working on it. If you’re really desperate to see some of our work please contact AHE directly: adrian-elcock@uiowa.edu. If you’re using Internet Explorer, the pages should work - they just may be unbelievably slow at times :(

For those still reading, we tend to jump around a bit in terms of our projects, but our current research falls into three main areas:

(1) Developing Brownian Dynamics (BD) methods to simulate very large macromolecular systems - this work involves modeling protein diffusion, association and folding events.

(2) Applying Molecular Dynamics (MD) methods to study the thermodynamics and kinetics of small biomolecular associations. This work is more chemical in nature; it provides quite fundamental insights into the nature of molecular interactions.

(3) Studying the interactions between small-molecule inhibitors and protein kinases. This is work that involves both computational and experimental efforts.

Department of Biochemistry

4-530 Bowen Science Building

51 Newton Road

Iowa City

IA 52242

To contact us: (e.g. if you want to tell us how useless this website is…)